Neurofibrillary tangles in pyramidal neuron, light micrograph


Light micrograph of a human cerebral cortex showing neurofibrillary tangles in a pyramidal neuron. Neurofibrillary tangles (NFTs) are a characteristic neuropathological lesion of Alzheimer's disease. They are composed of a highly-phosphorylated form of the microtubule-associated protein tau. Silver carbonate staining method.


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Photo credit: © JOSE CALVO / SCIENCE PHOTO LIBRARY / Alamy / Afripics
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