Most tumors are made up of many different types of cancer cells (tumor heterogeneity), which often harbor unique genetic mutations. Researchers want to determine how different subgroups of cancer cells within a tumor exhibit the ability of cancer cells to metastasize or develop resistance to therapeutic agents. This image of a mouse model of pancreatic cancer shows a multicolor lineage (and ampquotconfetti and ampquot) plot and demonstrates that a significant number of metastases presented from clusters of heterogeneous cells rather than outgrowth of single cells.


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Photo credit: © NIH / IMAGE POINT FR / BSIP / Alamy / Afripics
License: Licensed
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