Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . pillaries areruptured, and with thesputum the worm is swal-lowed, finally developing inthe duodenum. The trans-cutaneous infection is notthe only way by which theparasite may reach the intes-tine. Dirt-eaters may introduce the parasite in a form adapted to itsfurther development in the alimentary canal. The point of attachmentcorresponds to the area of maximum alkalinity of the bowel contents,extending from the second portion of the duodenum to the upper end ofthe ileum. The number of
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . pillaries areruptured, and with thesputum the worm is swal-lowed, finally developing inthe duodenum. The trans-cutaneous infection is notthe only way by which theparasite may reach the intes-tine. Dirt-eaters may introduce the parasite in a form adapted to itsfurther development in the alimentary canal. The point of attachmentcorresponds to the area of maximum alkalinity of the bowel contents,extending from the second portion of the duodenum to the upper end ofthe ileum. The number of parasites present may be enormous; Ernstfound 2768 in the intestine of a brick-maker. Sometimes the worm ishalf buried in the intestinal mucosa. The number found attached atautopsy is usually not large. Often small elevations with blood-marked punctures in the center indicate the points from which theparasites have become loosened. The lesions produced by the uncinaria may be brought about partly Report of the Commission for the Study and Treatment of Anemia in PortoRico, San Juan, Dec. i, 1904, p. Fig. 122.—Duodenum showing Attached , A. Papilla-like elevations with central depressions resultingfrom detachment of parasites. (Specimen presented tothe Museum of the Jefferson Medical College by Capt. Kieffer, U. S. A.) ANIMAL IAKASITKS AS CAfSKS Ol- DISEASE. 207 l)\ the loss of blood induced throuj^h tin. wounding of the < by the associated intlamniatory processes, which may not hemarked, and possiljly, to a certain extent, by the absorjjtion of meta-boHc products elaborated by the parasite. Allen J. Smith and Loebhave shown that the uncinaria of the dog protluces a hemolytic poison,and it is probable that some similar toxic substance is elaborated by thehook-worms in man. Ordinarily the amount of blood extracted cannot be large, although no doubt the continued loss of a small fjuantitymust exert considerable inlluence on the blood-makin
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