The Journal of nervous and mental disease . ween internal and external perimysium ; a small group ofmuscles fibres (as in one specimen ten) being surroundedby a layer of connective tissue fully as broad as the nor-mal perimysium externum. This latter, in the diseased muscle, is conspicuous by thepresence of arteries and veins, and of two kinds of bundlesof fibrous connective tissue, the one being the delicatefibrous tissue as seen in normal muscle, and the secondbeing broad and dense, resembling the fibrous connectivetissue of aponeuroses and fasciae. Besides this, the perimysium externum is,
The Journal of nervous and mental disease . ween internal and external perimysium ; a small group ofmuscles fibres (as in one specimen ten) being surroundedby a layer of connective tissue fully as broad as the nor-mal perimysium externum. This latter, in the diseased muscle, is conspicuous by thepresence of arteries and veins, and of two kinds of bundlesof fibrous connective tissue, the one being the delicatefibrous tissue as seen in normal muscle, and the secondbeing broad and dense, resembling the fibrous connectivetissue of aponeuroses and fasciae. Besides this, the perimysium externum is, in many places,crowded with or replaced by fat tissue. The general impression gained at the first glance is thatthe number of muscle-fibres is reduced, the mass of con- PSE UDOH YPER TPOPHIC PAPAL YS1S. 58l nective tissue, on the contrary, being decidedly aug-mented. These facts correspond to reports of all otherobservers, since first described by Duchenne, and fouryears later by Griesinger, and form the basis of the Fig. 2.—Quadriceps femoris from pseudo-hypertrophy. X 300. Longitudinal , Artery. K, Vein. C, Capillaries. TT, Tendon-like formations of fibrous con-nective tissue arisen from previous muscle-fibre. F, Fat globules in muscle-fibres. The question which, after such a view, forces itself uponthe mind is, Whence comes this augmented connectivetissue? 581 geo. w. jacoby. This question is, to my knowledge, not answeredsatisfactorily by any of the writers upon this speak of chronic interstitial connective-tissue hyper-plasia (Friedreich, Erb), proliferation of connective tis-sue (Buss), and Schultze describes the microscopicalpicture as being one in which the muscles are partly re-placed by normal fat and normal connective tissue, whilethe fibres themselves are partly in a state of simpleatrophy; and in another place, he speaks of the appear-ance of large connective-tissue tracts in the we see no satisfactory ex
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Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic
