Journal of Agricultural Research . sed centersX15. Reflected light. E.—Culture I, surface colonies, 10 days old, on +13 gelatin showing depressedcenters. X15. Reflected light. F.—Culture I, involution forms grown for nine days on beef agar at ^;i° C. X 1,500, G.—Culture V, beef-agar cultures stained with Ribberts capsule stain. X 1,900. H.—Culture II, 3-day-old, on -I-15 agar. Casares Gil stain. X 1,400. I.—Culture I, one-day culture on potato. Polar staining. Carbol fuchsin 1,700. FACTORS WHICH DETERMINE OTOCEPHALY IN GUINEA PIGS^ By Sewall Wright, Senior Animal Husbandman in Animal G
Journal of Agricultural Research . sed centersX15. Reflected light. E.—Culture I, surface colonies, 10 days old, on +13 gelatin showing depressedcenters. X15. Reflected light. F.—Culture I, involution forms grown for nine days on beef agar at ^;i° C. X 1,500, G.—Culture V, beef-agar cultures stained with Ribberts capsule stain. X 1,900. H.—Culture II, 3-day-old, on -I-15 agar. Casares Gil stain. X 1,400. I.—Culture I, one-day culture on potato. Polar staining. Carbol fuchsin 1,700. FACTORS WHICH DETERMINE OTOCEPHALY IN GUINEA PIGS^ By Sewall Wright, Senior Animal Husbandman in Animal Genetics, and OrsonN. Eaton, Scientific Assistatit in Animal Genetics, Animal Husbandry Division,United States Department of Agriculture INTRODUCTION Nearly all of the recognized types of monstrosities have appeared in thestock of guinea pigs maintained by the Bureau of Animal Industry forgenetic experimentation. The most abundant type, unless all thosewith leg or toe abnormahties are lumped together, has been that which. Fig. I.—Grades of otocephaly. Semidiagrammatic ventral views of the head and throat of the 12 grades ia coiaparison with the normal (o). Geoffroy Saint-Hilaire (7)^ called otocephalien in his classical mono-graph on the subject. Certain of the grades are of the well-knownCyclopean type. The most characteristic feature of these monsters is the close approachof the ears, there being in most cases but a single median opening in thethroat. There has been wide variation in the degree of defect, but allthe cases observed in our stock of guinea pigs fall practically into a single • Accepted for publication Aug. 3, 1923. • Reference is made by number (italic) to Literature cited, p. 180-181. Journal of Agricultural Research, Washington, D. C. ahb (161) Vol. XXVI, No. 4Oct. 27, 1933Key No. A—64 162 Journal of Agricultural Research voi. series of increasing defectiveness. Twelve grades, based on externalappearance, have been used. These are s
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