Molecule of the Antibiotic Penicillin, Derived from the Fungus Penicillium


Penicillin (sometimes abbreviated PCN or pen) is a group of antibiotics derived from Penicillium fungi. Penicillin antibiotics are historically significant because they were the first drugs that were effective against many previously serious diseases such as tuberculosis, syphilis, and staphylococcus infections. Penicillins are still widely used today, though many types of bacteria are now resistant. All penicillins are Beta-lactam antibiotics and are used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. The discovery of penicillin is attributed to Scottish scientist and nobel laureate Alexander Fleming in 1928. He showed that if Penicillium notatum was grown in the appropriate substrate, it would exude a substance with antibiotic properties, which he dubbed penicillin.


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