The medical diseases of children . ial changes from a macroscopic examination alone. The musclemay appear pale, and perhaps slightly greasy. There is, of course,much enlargement of the heart, and usually there are evidences ofvalvular and pericardial inflammation. The histological changes* are of great importance, and are as arule very characteristic. There is a fatty change in the parenchy-matous cells, most marked in the most vascular parts of the cardiacmuscle—namely, close to the endocardium and pericardium. Thepapillary muscles are much affected. This change is probably forthe most part d


The medical diseases of children . ial changes from a macroscopic examination alone. The musclemay appear pale, and perhaps slightly greasy. There is, of course,much enlargement of the heart, and usually there are evidences ofvalvular and pericardial inflammation. The histological changes* are of great importance, and are as arule very characteristic. There is a fatty change in the parenchy-matous cells, most marked in the most vascular parts of the cardiacmuscle—namely, close to the endocardium and pericardium. Thepapillary muscles are much affected. This change is probably forthe most part due to a toxaemia. Pericapillary collections ofleucocytes, mainly polymorphonuclear, are seen, and are most likelychiefly the result of cedema due to venous congestion. Of great interest are certain nodules found in the stroma. Thesewere first discovered by Aschoff, and have been re-described by Dr. * This account is founded upon Dr. Carey Coombs article in the Quar. Jour, of Med., Vol. ii., No. 5. ACUTE RHEUMATIC MYOCARDITIS 371. Fig. 61.—Rheumatic Myocarditis. A, Large cells grouped together to constitutesubiniliary nodule. B, Small-celled infiltration at periphery of nodule. C Arteriole in closerelation with nodule. D, Cardiac muscle. Eyepiece, 2 Leitz ; objective, \ in. Leitz.


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectpediatrics, bookyear1