Lewy body in neuron in Parkinson's disease, illustration. Lewy bodies are abnormal aggregates of protein that develop inside nerve cells (blue) in Par
Lewy body in neuron in Parkinson's disease, illustration. Lewy bodies are abnormal aggregates of protein that develop inside nerve cells (blue) in Parkinson's disease. Here, a classical Lewy body (pink) is shown as an eosinophilic cytoplasmic inclusion consisting of a dense core surrounded by a halo of fibrils, the primary structural component of which is alpha-synuclein. The Lewy body displaces other cell components. This neuron is in a brain region known as the substantia nigra. Lewy bodies are thought to cause the progressive degeneration of the neurons that leads to the symptoms of Parkinson's. These symptoms include, tremor, muscular rigidity, poor balance and depression. A normal neuron is at lower left.
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Photo credit: © RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
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