A technique called in situ hybridization shows whether a gene is expressed in cells and also provides clues about the function of the gene. This technique has helped identify activated oncogenes in cancer cells and their normal counterparts in normal cells, in many different species. In this photograph, a labeled segment of DNA (a known oncogene) has been placed into a mouse oocyte, a cell that develops into a mature egg. The labeled DNA paired with (or hybridized to) multiple copies of RNA in the mouse oocyte.

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Photo credit: © NIH / IMAGE POINT FR / BSIP / Alamy / Afripics
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