Illustration of a cholesterol molecule (spheres) binding to the G-protein coupled receptor (GPCR) Ste2 from the yeast Saccharomyces cerevisiae. Sre2 is a yeast mating receptor that binds pheromone molecules. Binding of a pheromone induces a signalling cascade that prepares the cell for sexual reproduction. The receptor is being studied as possible drug target for fungal infections.

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Photo credit: © FRANCISCO J. ENGUITA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No

Keywords: -, -protein, 3d, artwork, binding, biochemical, biochemistry, biological, cerevisiae, cholesterol, class, coupled, dimensional, dimer, fungal, fungus, gpcr, homodimer, illustration, mating, medical, medicine, model, molecular, molecule, pathway, pheromone, pheromone-induced, protein, receptor, response, saccharomyces, ste2, structure, transmembrane, yeast